{"id":5896,"date":"2023-07-20T11:15:55","date_gmt":"2023-07-20T11:15:55","guid":{"rendered":"https:\/\/mysourcefunding.com\/startups\/personalized-medicine-the-evolution-of-healthcare\/"},"modified":"2023-07-20T11:15:55","modified_gmt":"2023-07-20T11:15:55","slug":"personalized-medicine-the-evolution-of-healthcare","status":"publish","type":"post","link":"https:\/\/mysourcefunding.com\/?p=5896","title":{"rendered":"Personalized Medicine: The Evolution Of Healthcare"},"content":{"rendered":"<div>\n<p><em>Jacob Kupietzky is President of <\/em><em data-ga-track=\"ExternalLink:https:\/\/www.hcthealthcare.com\/\">HealthCare Transformation<\/em><em>, a company dedicated to providing hospitals with experienced interim executives. <\/em><\/p>\n<p>One of healthcare\u2019s biggest challenges has always been its lack of precision. If a patient were to ask if a prescribed treatment will be effective, the doctor can only respond with generalities: \u201cWell, in this 2013 study, X percent of patients exhibited Y range of outcomes with Z percent significance.\u201d This is far from a criticism of my profession; each patient brings with them so much variability\u2014be it genetic, behavioral, environmental, demographic or countless other factors\u2014that the best doctors can do is provide only generalized treatment recommendations.<\/p>\n<p>At least, that\u2019s how healthcare used to be\u2014before the advent of personalized medicine.<\/p>\n<h2 class=\"subhead-embed color-accent bg-base font-accent font-size text-align\"><strong>Personalized Medicine And Big Data<\/strong><\/h2>\n<p>Advancements in technology have created incredible amounts of data in all areas of our lives. The idea behind personalized medicine is that practitioners can take advantage of this patient information to determine &#8220;which approaches will be effective for which patients based on genetic, environmental and lifestyle factors,&#8221; to borrow a phrase from the<strong> <\/strong>National Library of Medicine. When this concept was in its infancy a few years ago, practitioners were limited to such data sources as medical images and patient histories. Today, the variety of sources of patient data is astounding.<\/p>\n<p><fbs-ad position=\"inread\" progressive=\"\" ad-id=\"article-0-inread\" aria-hidden=\"true\" role=\"presentation\"><\/fbs-ad><\/p>\n<p>\u2022 DNA testing. The amount of publicly available genomic data is so vast, it is surpassing that of astronomy.<\/p>\n<p>\u2022 Medical imaging at the subcellular level, plus its metadata.<\/p>\n<p>\u2022 Diagnostic and treatment information provided in electronic health records.<\/p>\n<p>\u2022 Insurance claim and pharmacy refill information.<\/p>\n<p>\u2022 Data from home testing kits, such as hormone levels, allergies, food sensitivity and vitamin deficiencies.<\/p>\n<p>\u2022 Behavioral and biological data via wearable devices. These days, your Apple watch can do more than tell time\u2014it can count your steps, track your heart rate and even record an echocardiogram.<\/p>\n<h2 class=\"subhead-embed color-accent bg-base font-accent font-size text-align\"><strong>Personalized Medicine In Practice<\/strong><\/h2>\n<p>So how can all this information inform personalized medicine? By harnessing all of these data points, we can better match the right treatment plans to the right patients. Consider the following examples.<\/p>\n<p>\u2022 In a 2017 study in Translational Medicine &amp; Research, the authors discuss how data from wearable monitors, such as out-of-office blood pressure readings and at-home exercise readings, can be used to create treatment plans for preventing hypertension. The same article asserts that by mining omics data, phenotype data, social media, insurance claims information and electronic medical records, practitioners can better create treatment plans to address cardiovascular disease before acute myocardial infarction.<\/p>\n<p>\u2022 In this 2018 study published in BMC Medicine, the authors discuss how by integrating molecular profiling with drug-gene interactions, doctors can remove from consideration cancer treatment options that are ineffective or cause adverse events.<\/p>\n<p>\u2022 In a 2017 study in Frontiers in Pharmacology, researchers used genetic screening to identify the phenotype of patients with cystic fibrosis. By understanding each patient\u2019s phenotype, doctors can adjust the treatment targeting cystic fibrosis symptoms.<\/p>\n<h2 class=\"subhead-embed color-accent bg-base font-accent font-size text-align\"><strong>Understanding Costs<\/strong><\/h2>\n<p>While personalized care at first blush sounds like a prohibitively expensive proposition, I believe the idea behind it is actually likely to lower the costs of care. By trading the costs of acquiring and managing data for the costs of unnecessary and imprecise treatment plans, the use of big data can create better outcomes faster. As personalized medicine advances, we can expect to find less trial and error, an increase in preventative procedures and a decrease in corrective treatments.<\/p>\n<h2 class=\"subhead-embed color-accent bg-base font-accent font-size text-align\"><strong>Potential Challenges<\/strong><\/h2>\n<p>This kind of personalized care is still a developing trend, and as with any paradigm shift, there are several obstacles that need to be addressed.<\/p>\n<p><strong>\u2022 Data Management:<\/strong> Storing and processing increasingly large amounts of data can be challenging. The more data we have, the harder it is to make that data FAIR\u2014findable, accessible, interoperable and reusable.<\/p>\n<p><strong>\u2022 Data Noise:<\/strong> Sorting through data and understanding the story it is telling you can be challenging, especially when multiple data points (with multiple sample sizes and procedural rigor) are telling conflicting stories. The more data we receive, the more important proper data interpretation becomes.<\/p>\n<p><strong>\u2022 Privacy Concerns: <\/strong>Any conversation about data should be accompanied by one about who owns the data (are medical institutions owners of the data, or merely custodians?) and how that data can be used.<\/p>\n<p><strong>\u2022 Patient Expectations:<\/strong> With more data becoming available to patients (such as through wearable monitors and at-home testing), patients have greater ability to self-diagnose, without medical training or expertise\u2014and agency to act on those self-diagnoses.<\/p>\n<p>That last challenge truly reinforces the role of the physician and the importance of the doctor-patient relationship. Whether we like it or not, our patients have more access to their own health and biological information than they have ever had before.<\/p>\n<p>Our role isn\u2019t to downplay that information in an effort to increase our own prestige, however. We should put it in the correct context, for sure, but ultimately use that data to create better patient outcomes. With an increase in data comes an increase in expectations, and we must be up to that challenge.<\/p>\n<p>Forbes Business Council is the foremost growth and networking organization for business owners and leaders. <em data-ga-track=\"InternalLink:https:\/\/councils.forbes.com\/qualify?utm_source=forbes.com&amp;utm_medium=referral&amp;utm_campaign=forbes-links&amp;utm_term=fbc&amp;utm_content=in-article-ad-links\">Do I qualify?<\/em><\/p>\n<\/div>\n<p>Read the full article <a href=\"https:\/\/www.forbes.com\/sites\/forbesbusinesscouncil\/2023\/07\/19\/personalized-medicine-the-evolution-of-healthcare\/\" target=\"_blank\" rel=\"noopener\">here<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jacob Kupietzky is President of HealthCare Transformation, a company dedicated to providing hospitals with experienced interim executives. One of healthcare\u2019s biggest challenges has always been its lack of precision. If a patient were to ask if a prescribed treatment will be effective, the doctor can only respond with generalities: \u201cWell, in this 2013 study, X [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5897,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[77],"tags":[],"class_list":{"0":"post-5896","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-startups"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Personalized Medicine: The Evolution Of Healthcare | Brandiary<\/title>\n<meta name=\"description\" content=\"Jacob Kupietzky is President of HealthCare Transformation, a company dedicated to providing hospitals with experienced interim executives. 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